Ingredient profile
Alpha-GPC in Neuro Recall: What Choline Research Shows and How Much Is Inside
Alpha-GPC is a choline compound listed ninth of ten in Neuro Recall's 635 mg blend, so it can be at most about 70 mg. Research found it may help thinking in people with dementia at 1,200 mg a day, but it has not been studied in healthy people, and no long-term safety studies exist (ADDF, Alpha-GPC).
Written by the Neuro Recall editorial teamUpdated
Label facts
What is alpha-GPC in Neuro Recall?
Alpha-GPC, short for alpha-glycerophosphorylcholine, is a source of choline. The label calls it "GPC Choline" and places it ninth in the blend, just before lutein and zeaxanthin.
| Label name | GPC Choline (α-Glycerophosphorylcholine) |
|---|---|
| Scientific name | Choline alfoscerate |
| What it is | Choline compound |
| Position in the list | 13 of 14 (blend ingredients are listed from most to least by weight; the four vitamins and minerals come first with amounts) |
| Per serving (2 capsules) | Not disclosed (part of the 635 mg blend) |
| Amount used in research | 1,200 mg a day in Alzheimer's trials; none in healthy people |
| Strength of evidence | Only studied in dementia |
| Traditional or marketed use | Choline source sold for focus |
| Main caution | Heartburn, headache, insomnia and dizziness reported; few long-term safety data. |
Researchers also call it choline alfoscerate. Supplement makers sell it for focus, and brand panels for Neuro Recall speak of "mental clarity and focus." Those are marketing words, not test results.
The research
What are the benefits of alpha-GPC?
For healthy adults, nobody knows, because no studies have tested them. In people with dementia, 1,200 mg a day may improve thinking (ADDF, Alpha-GPC).
That split matters. Neuro Recall is sold for memory and focus support to adults without a diagnosis, the very group with no alpha-GPC data.
| Group | Amount studied | What was found |
|---|---|---|
| People with dementia | 1,200 mg a day, as 400 mg three times | May improve cognition |
| Healthy adults | Not studied | No data |
| Long-term use | Not studied | No long-term safety studies |
| Neuro Recall users | Not printed (about 70 mg at most) | No trial of the formula |
By the numbers
Alpha-GPC in research versus the Neuro Recall blend
The dementia trials gave three doses a day. The blend's share is a small slice of one.
Amount
How much alpha-GPC is in Neuro Recall?
The label does not say, but the order sets a ceiling. With eight heavier items ahead of it, alpha-GPC can weigh no more than a ninth of 635 mg, about 70 mg.
That is under 6% of the 1,200 mg daily dose in the dementia trials. It is also well below a single 400 mg trial dose. The real amount may be lower still, since blends list items from most to least by weight (FDA, Labeling guide).
Whatever alpha-GPC adds, it is not the amount researchers tested. Treat it as a minor part of the formula.
Tolerance
What are the side effects of alpha-GPC?
Eight are reported: constipation, nervousness, heartburn, headache, insomnia, dizziness, rash and confusion (ADDF, Alpha-GPC). No study measured them at an amount as small as the Neuro Recall share.
Gut
Constipation and heartburn.
Sleep and nerves
Insomnia and nervousness.
Head
Headache, dizziness and confusion.
Skin
Rash.
New confusion is never something to blame on a supplement and wait out. Sudden confusion with trouble speaking or one-sided weakness can be a stroke: call 911 (CDC, Stroke signs).
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Alpha-GPC vs CDP choline: what is the difference?
They are two different choline compounds. CDP choline is also sold as citicoline, while alpha-GPC is choline alfoscerate.
Our source covers alpha-GPC only, so we will not rank one above the other. Neuro Recall contains alpha-GPC and no CDP choline. If a product page claims one form "works better," ask which study it means.
When you compare any choline product, check three things:
- The exact form named on the label, such as alpha-GPC or citicoline
- A printed milligram amount, not a share of a blend
- Whether the research behind it used people like you
Neuro Recall passes the first check and misses the second. On the third, the only alpha-GPC trials involved people with dementia.
Combinations
Can you take L-theanine with alpha-GPC?
Neuro Recall already does: both sit in the same blend. No study in our sources tested the pair together.
They pull in different directions on paper. L-theanine may add to drowsiness with sedatives (MSKCC, L-theanine), while alpha-GPC has insomnia and nervousness among its reported effects. Green tea extract adds some caffeine as well (NCCIH, Green tea). Notice how you sleep in the first weeks, and tell your doctor about any sleep medicine you use.
Compare
Where does alpha-GPC fit in the Neuro Recall formula?
Near the bottom, in both weight and evidence. Bacopa and ginkgo sit higher in the blend and have more human research. Alpha-GPC adds a choline source with dementia-only data.
| Ingredient | Place in blend | Most it can be | What research tested |
|---|---|---|---|
| Ginkgo biloba | 2 of 10 | About 317 mg | Dementia risk in large studies, one in adults 75 and older; no effect (NCCIH, Ginkgo) |
| Bacopa monnieri | 4 of 10 | About 158 mg | Usually 300 mg a day; small gains (ADDF, Bacopa) |
| Alpha-GPC | 9 of 10 | About 70 mg | 1,200 mg a day in dementia (ADDF, Alpha-GPC) |
FAQ
Alpha-GPC in Neuro Recall: common questions
Is alpha-GPC a form of choline?
Yes. Alpha-GPC is a choline compound, also called choline alfoscerate, and the Neuro Recall label lists it as GPC choline (ADDF, Alpha-GPC). It is the ninth of ten items in the 635 mg blend, so the amount of choline it supplies is small and not printed.
What is the right alpha-GPC dosage?
Dementia trials used 1,200 mg a day, split into 400 mg three times (ADDF, Alpha-GPC). No dose is set for healthy adults, because no studies have tested them. Neuro Recall holds at most about 70 mg, and the exact amount is not printed on the label.
Does alpha-GPC cause insomnia?
It can. Insomnia, nervousness and headache are among its reported side effects (ADDF, Alpha-GPC). If your sleep gets worse after starting Neuro Recall, try taking both capsules in the morning, since the label names no time, and stop if the problem continues.
Is alpha-GPC safe long term?
Nobody knows yet. There are no long-term safety studies of alpha-GPC (ADDF, Alpha-GPC). If you plan to take Neuro Recall for many months, review it with your doctor at your next visit, and stop if new symptoms such as confusion or dizziness appear.
Does alpha-GPC help focus in healthy people?
There is no answer yet, because it has not been studied in healthy people (ADDF, Alpha-GPC). The only promising data come from people with dementia at 1,200 mg a day. Any focus claim for healthy adults rests on marketing, not trials.
Can alpha-GPC help with ADHD?
Our source lists no ADHD research, and Neuro Recall is not a treatment for ADHD or any other condition. Attention problems deserve a proper medical evaluation. Keep taking your prescribed medicine, and never stop or change a dose on your own.
Does Neuro Recall contain choline?
Yes, through alpha-GPC, which the label lists as GPC choline. It is not shown as a separate choline line with a Daily Value, and its amount is hidden in the 635 mg blend. If you track choline from food or other supplements, count this one as a small, unknown amount.
Who wrote this
Written and reviewed by
Plain-language pages built from the label, the sales page and linked public health sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by a U.S. merchant that sells Neuro Recall, not by the manufacturer (the label carries the FYVUS logo). We earn money when you buy through our order links.
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